Massachusetts Turnpike (I-90)
Take the Mass Pike/Route 90 East towards Boston to the "Brighton, Cambridge" exit. (exit #18).
Bear right after the tollbooth and follow the sign for Cambridge.
Continue straight over the River Street Bridge.
At the bottom of the bridge, take an immediate left onto Memorial Drive.
At the third traffic light, turn right onto J.F. Kennedy Street and then turn left at the first light onto Eliot Street.
Bear left at the next intersection onto Bennett Street and The Charles Hotel is immediately on your left.